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Iodine status of euthyroid adults: A cross-sectional, multicenter study
Danchen Wang1, Songlin Yu1, Yicong Yin1
1Department of Clinical Laboratory, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Science, Beijing, China.
Journal of Clinical Laboratory Analysis
|February 10, 2019
Summary
Healthy Chinese adults generally have sufficient iodine levels, with a 33.1% prevalence of iodine deficiency. Further research is needed to understand the relationship between urinary iodine concentration and thyroid hormone levels.
Area of Science:
- Endocrinology
- Nutrition Science
- Public Health
Background:
- Iodine is crucial for thyroid hormone synthesis and thyroid function.
- Assessing iodine nutrition status is vital for public health.
- Thyroid health is directly linked to adequate iodine intake.
Purpose of the Study:
- To evaluate the iodine nutrition status in healthy Chinese adults.
- To determine the prevalence of iodine deficiency in this population.
- To investigate the association between urinary iodine concentration and thyroid hormone levels.
Main Methods:
- A cross-sectional, multicenter study involving 1017 healthy Chinese adults.
- Urinary iodine concentration (UIC) measured using inductively coupled plasma mass spectroscopy.
- Thyroid ultrasonography and thyroid hormone levels (including TSH) assessed.
Main Results:
- Median UIC was 134.0 µg/L, indicating generally sufficient iodine levels.
- A 33.1% prevalence of iodine deficiency was observed based on WHO criteria.
- Serum TSH levels showed an increasing trend with higher UIC, but no significant differences in thyroid hormones were found across different UIC levels.
Conclusions:
- Healthy Chinese adults with normal thyroid structures exhibit relatively sufficient iodine levels.
- A notable prevalence of iodine deficiency exists, warranting attention.
- The direct correlation between UIC and thyroid hormone levels requires further investigation.
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