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No inflammatory benefit obtained by single-incision laparoscopic surgery for right hemicolectomy compared with

Masayasu Hara1, Kazuyoshi Shiga2, Takeshi Yanagita2

  • 1Department of Gastroenterological Surgery, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan. mshara@med.nagoya-cu.ac.jp.

Surgery Today
|February 11, 2019
PubMed
Abstract

Insights

Single-incision laparoscopic surgery (SILS) for right hemicolectomy showed no systemic inflammatory advantage over traditional multi-port laparoscopic surgery (MLS). Both techniques demonstrated feasibility, but SILS had fewer harvested lymph nodes.

Area of Science:

  • Colorectal Surgery
  • Minimally Invasive Surgery
  • Surgical Oncology

Background:

  • Single-incision laparoscopic surgery (SILS) is an evolving minimally invasive technique.
  • Comparing SILS with traditional multi-port laparoscopic surgery (MLS) is crucial for understanding its clinical benefits.
  • Inflammatory response is a key indicator of surgical stress and recovery.

Purpose of the Study:

  • To compare the perioperative inflammatory mediators between SILS and MLS for right hemicolectomy.
  • To evaluate the feasibility and postoperative inflammatory response of SILS versus MLS.
  • To assess key surgical outcomes including operation duration, blood loss, and lymph node harvest.

Main Methods:

  • Retrospective analysis of 56 consecutive patients undergoing right hemicolectomy.
  • Comparison between 20 patients in the SILS group and 36 patients in the MLS group.
  • Measurement of plasma vascular endothelial growth factor (VEGF), serum interleukin-6 (IL-6), C-reactive protein (CRP), and platelet count pre- and postoperatively.

Main Results:

  • No conversions to open surgery in either group.
  • SILS was associated with a longer operation duration but potentially lower blood loss compared to MLS.
  • No significant differences in perioperative inflammatory mediators (VEGF, IL-6, CRP) were observed between SILS and MLS groups.
  • Significantly fewer lymph nodes were harvested in the SILS group.

Conclusions:

  • Single-incision laparoscopic surgery (SILS) does not offer a systemic inflammatory advantage over multi-port laparoscopic surgery (MLS) for right hemicolectomy.
  • While feasible, SILS may compromise lymph node retrieval compared to MLS.
  • Further research is needed to optimize SILS techniques for oncologic adequacy.
Keywords:
IL-6Right hemicolectomySILSSystemic inflammation

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