Related Experiment Video
Updated: Jan 29, 2026

Surgery and Behavioral Testing in the Tibial Neuroma Transposition Model in Rats
Published on: January 6, 2023
[Application of proximal tibial hemiprosthesis replacement and second-stage revision for proximal tibial osteosarcoma
Yuan Li1, Hairong Xu1, Huachao Shan1
1Department of Orthopedic Oncology Surgery, Beijing Ji Shui Tan Hospital, Beijing, 100035, P.R.China.
Objective:
To investigate the feasibility and effectiveness of proximal tibial hemiprosthesis replacement in the first stage and prosthesis revision in the second stage in reducing the risk of length discrepancy of limbs in children with proximal tibial osteosarcoma.
Methods:
Between 2009 and 2013, 3 children with conventional osteosarcoma at the proximal tibia (stage ⅡB) were treated. There were 2 boys and 1 girl. They were 12, 13, and 13 years old, respectively. After 4 courses of preoperative chemotherapy, the proximal tumor segmental resection and proximal tibial hemiprosthesis replacement were performed. Then the patients underwent prosthetic revision in the second stage when they were 20, 17, and 17 years old, respectively.
Results:
All patients successfully completed two stages of operations. The length discrepancy of lower limb after the second stage operation were 19, 7, and 21 mm, respectively. Three patients were followed up 13, 3, and 27 months after the second stage operation, and the lower extremities functions were satisfactory. The Musculoskeletal Tumor Society (MSTS) score was 26, 27, and 25, respectively.
Conclusion:
The proximal tibial hemiprosthesis replacement in the first stage combined with prosthesis revision in the second stage for treating the proximal tibia osteosarcoma in children can keep the distal femur growth ability, reduce the length discreapancy of lower limb, and obtain satisfactory stability and good function.
Related Concept Videos
Factors Influencing Attraction I: Proximity
Continuous Renal Replacement Therapy
Stages of Infection
Stages of General Anesthesia
Stages of Sleep
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
Drug Dosing: Infants and Children

