Aurone: A biologically attractive scaffold as anticancer agent

Abdulrahman Alsayari1, Abdullatif Bin Muhsinah1, Mohd Zaheen Hassan1

  • 1College of Pharmacy, King Khalid University, Abha, 62529, Saudi Arabia.

Related Concept Videos

Noncovalent Attractions in Biomolecules02:35

Noncovalent Attractions in Biomolecules

Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
64.8K
Noncovalent Attractions in Biomolecules02:35

Noncovalent Attractions in Biomolecules

19.5K
Factors Influencing Attraction II: Physical Attraction01:21

Factors Influencing Attraction II: Physical Attraction

Physical attractiveness plays a crucial role in shaping interpersonal attraction, influencing first impressions, social interactions, and long-term relationship dynamics. Psychological research consistently demonstrates that attractiveness affects social evaluations and behavioral outcomes in various contexts.Influence on Social InteractionsResearch has shown that individuals perceived as physically attractive often experience preferential treatment in social and professional settings. One...
247
Local Attraction01:22

Local Attraction

Local attraction refers to disturbances in compass readings caused by magnetic influences from nearby objects such as metal fences, buried pipes, vehicles, buildings, power lines, or natural iron ore deposits. Small items like wristwatches, steel tools, or belt buckles can also interfere with the compass by creating local magnetic fields that distort the Earth's natural magnetic field. These distortions lead to inaccurate readings, posing navigation and land surveying challenges.Local...
376
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF01:24

Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF

Tumor Necrosis Factor (TNF), a proinflammatory cytokine, contributes significantly to the inflammation seen in Crohn's disease. It exists as soluble TNF and membrane-bound TNF, with actions mediated through TNF receptors (TNFR). TNFR activation leads to the release of proinflammatory cytokines, T-cell activation, collagen production, and leukocyte migration, all contributing to inflammation in Crohn's disease. Anti-TNF monoclonal antibodies, namely infliximab (Remicade), adalimumab...
548
Understanding Interpersonal Attraction01:25

Understanding Interpersonal Attraction

Interpersonal attraction is a fundamental psychological phenomenon influencing human relationships across various contexts. It refers to one person's positive feelings or interests toward another, serving as the foundation for friendships, romantic partnerships, familial bonds, and professional relationships. The nature of interpersonal attraction extends beyond romantic connections, shaping interactions in both short-term and long-term social engagements.Psychological Foundations of...
298