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Updated: Jan 29, 2026

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
Published on: December 1, 2016
Aurone: A biologically attractive scaffold as anticancer agent
Abdulrahman Alsayari1, Abdullatif Bin Muhsinah1, Mohd Zaheen Hassan1
1College of Pharmacy, King Khalid University, Abha, 62529, Saudi Arabia.
Abstract:
Aurones are very simple, promising anticancer lead molecules containing three rings (A, B and C). A very slight structural variation in the aurones elicits diverse affinity and specificity towards different molecular targets. The present review discusses the design, discovery and development of natural and synthetic aurones as small molecule anticancer agents. Detailed structure-activity relationship and intermolecular interactions at different targets are also discussed. Due to their rare occurrence in nature and minimal mention in literature, the anticancer potential of aurones is rather recent but in constant progress.
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