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Updated: Jan 29, 2026
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Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
Published on: January 25, 2015
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Amelanocytic anorectal malignant melanoma-Case report
Marta Serra1, Teresa Santos1, Margarida Martins1
1Centro Hospitalar do Baixo Vouga - Av. Artur Ravara, 3810 - 501 Aveiro, Portugal.
International Journal of Surgery Case Reports
|February 12, 2019
Summary
Anorectal malignant melanoma (AMM) is rare and aggressive. Wide local excision (WLE) offers comparable survival to abdominal perineal resection (APR) with fewer complications.
Area of Science:
- Oncology
- Surgical Oncology
- Gastroenterology
Background:
- Anorectal malignant melanoma (AMM) is a rare, aggressive malignancy.
- It constitutes less than 2% of all melanomas and anal tumors.
- AMM predominantly affects individuals in their 6th-7th decades, with a higher incidence in women.
Purpose of the Study:
- To evaluate treatment strategies for Anorectal Malignant Melanoma (AMM).
- To compare the outcomes of Wide Local Excision (WLE) versus Abdominal Perineal Resection (APR).
Main Methods:
- A case presentation of an 82-year-old male with Stage I AMM.
- Initial treatment involved local excision.
- Disease recurrence and metastasis were observed within a year, leading to mortality at 32 months.
Main Results:
- The case highlights the aggressive nature of AMM, even at an early stage.
- Despite initial treatment, local recurrence and distant metastasis occurred.
- The patient's survival was limited to 32 months post-diagnosis.
Conclusions:
- Optimal treatment for AMM remains controversial due to limited prospective studies.
- Wide Local Excision (WLE) demonstrates comparable survival rates to Abdominal Perineal Resection (APR).
- WLE is associated with faster recovery and fewer postoperative complications compared to APR.
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