Related Experiment Video
Updated: Jan 29, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
Pediatric idiopathic retroperitoneal fibrosis
Ashwin V Subramani1, Gina M Lockwood2, Jennifer G Jetton3
1Roy J. and Lucille A. Carver College of Medicine, 01334C PFP, 200 Hawkins Drive, Iowa City, IA 52242, US.
Idiopathic retroperitoneal fibrosis (RPF) is exceptionally rare in children. This case highlights MRI
Area of Science:
- Pediatric Nephrology
- Radiology
- Rare Diseases
Background:
- Retroperitoneal fibrosis (RPF) is a rare condition.
- Pediatric RPF is exceedingly rare, with most cases having secondary causes.
Observation:
- An 11-year-old female presented with severe bilateral hydronephrosis.
- Initial diagnosis was made via retroperitoneal ultrasound.
Findings:
- Magnetic resonance imaging (MRI) confirmed idiopathic retroperitoneal fibrosis.
- This diagnosis was established in an 11-year-old Caucasian female.
Implications:
- Highlights the importance of considering RPF in pediatric obstructive urinary findings.
- Emphasizes MRI's utility in diagnosing and monitoring pediatric RPF.
- Underscores the rarity of idiopathic pediatric RPF.
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