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Isolation and In Vitro Culture of Murine and Human Alveolar Macrophages
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Isolated Cerebral Alveolar Echinococcosis.

Aurélie Baldolli1,2, Julie Bonhomme3, Hélène Yera4

  • 1Infectious Diseases Department, CHU de Caen, Caen, France.

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|February 12, 2019
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Summary

Cerebral alveolar echinococcosis (AE), typically involving the liver, is rarely found in the brain. This case highlights a unique instance of extensive cerebral AE mimicking other parasitic infections, even without liver disease.

Keywords:
Echinococcus multilocularisabscesscerebralprimary lesion

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Area of Science:

  • Neuroparasitology
  • Neurology
  • Radiology

Background:

  • Cerebral alveolar echinococcosis (AE) is an uncommon parasitic infection of the brain.
  • AE typically involves the liver, with central nervous system involvement being rare.
  • Differentiating cerebral AE from other conditions like neurocysticercosis can be challenging.

Purpose of the Study:

  • To report an exceptional case of primary cerebral alveolar echinococcosis.
  • To describe the clinical presentation and imaging findings of a rare brain infection.
  • To discuss the diagnostic challenges in differentiating cerebral AE from neurocysticercosis.

Main Methods:

  • Case report of a 62-year-old male patient.
  • Review of clinical history, neurological examination, and neuroimaging findings.
  • Differential diagnosis considerations including neurocysticercosis.

Main Results:

  • The patient presented with over 100 cerebral lesions.
  • The cerebral lesions mimicked neurocysticercosis on imaging.
  • No evidence of liver involvement was found, which is atypical for AE.
  • The patient had a history of hereditary hemorrhagic telangiectasia.

Conclusions:

  • Primary cerebral alveolar echinococcosis can present with a high burden of lesions mimicking other parasitic infections.
  • Absence of liver involvement does not exclude AE in rare cases.
  • Hereditary hemorrhagic telangiectasia may be a co-occurring condition.