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Updated: Jan 29, 2026

Establishing a Diaphyseal Femur Fracture Model in Mice
Published on: December 9, 2022
[Fractures of the patella]
1Chirurgisch-Traumatologisches Zentrum, Asklepios Klinik St. Georg, Hamburg, Deutschland.
Abstract:
With 1% of all skeletal fractures patellar fractures are rare. The majority of cases are caused by a direct trauma to the flexed knee. The diagnosis is made via the injury mechanism as well as the physical and radiological findings. In conventional x‑ray imaging the extent of injury often is underrated, which mostly leads to the necessity of a computed tomography (CT) scan. The aim of the treatment is the reconstruction of the extensor mechanism and the anatomical reconstruction of the articular surface. The type of treatment depends on the fracture type. Tension band wiring still is the most frequently practiced technique. Complications, such as secondary dislocation or migration of the K‑wires resulting in revision surgery have been described in up to 30% of the cases. Studies could already show a higher biomechanical stability of osteosynthesis via cannulated screws. Especially in cases of comminuted fractures, osteosynthesis via a locking plate seems to have several advantages but long-term results are not yet available.
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Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...

