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Updated: Jan 29, 2026

Sample Drift Correction Following 4D Confocal Time-lapse Imaging
Published on: April 12, 2014
Time-Lapse Technologies and 4D Imaging of Kidney Development
Ulla Saarela1,2,3, Ilya Skovorodkin4,5,6
1Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland. ulla.saarela@oulu.fi.
Time-lapse imaging allows studying embryonic kidney development ex vivo. This technique tracks morphogenesis in four dimensions (3D + time) using advanced microscopy.
Area of Science:
- Developmental biology
- Microscopy techniques
Background:
- Embryonic kidney development can be studied ex vivo.
- Time-lapse imaging facilitates observing dynamic biological processes.
Purpose of the Study:
- To investigate embryonic kidney morphogenesis using time-lapse imaging.
- To apply advanced 3D imaging for developmental studies.
Main Methods:
- Culturing dissected embryonic kidneys ex vivo.
- Utilizing onstage microscopy incubators for live imaging.
- Employing confocal and 3D imaging systems.
Main Results:
- Successfully captured dynamic changes during kidney development.
- Enabled four-dimensional (3D + time) tracking of morphogenesis.
- Demonstrated the feasibility of studying developmental processes in real-time.
Conclusions:
- Time-lapse imaging is effective for studying embryonic kidney morphogenesis.
- Four-dimensional imaging provides unprecedented insights into developmental biology.
- This approach enhances our understanding of organogenesis.
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08:23Time-lapse Live Imaging and Quantification of Fast Dendritic Branch Dynamics in Developing Drosophila Neurons
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