Related Experiment Video
Updated: Jan 29, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Erdheim-Chester disease mimicking multiple sclerosis or a new association?
José Manuel Sánchez-Villalobos1, Amaya Jimeno-Almazán2, Carmen López-Peña3
1Department of Neurology, Santa Lucía University Hospital, Cartagena, Spain.
Abstract:
Erdheim-Chester disease (ECD) is a rare form of non-Langerhans cell histiocytosis that presents potential impairment of the central nervous system (CNS). Frequent CNS impairment makes ECD a disease worth considering in the differential diagnosis of multiple sclerosis (MS). We report the case of a patient initially diagnosed with relapsing-remitting MS with an atypical course who developed ECD during the disease progression. Given the patient's clinical-radiological characteristics, two diagnostic possibilities were proposed: the coexistence of both diseases or a new presentation of ECD mimicking MS. We conducted a literature review, analyzing the various diagnostic and therapeutic possibilities.
Related Concept Videos
Association Areas of the Cortex
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Associative Learning
Classical conditioning, also known...
Multiple Allele Traits
Somatosensory, Motor, and Association Cortex
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Regulation of Expression Occurs at Multiple Steps
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...

