Postmenopausal osteoporosis: an update on current and future therapeutic options
Pauline M Camacho1, Reina Armamento-Villareal2, Michael Kleerekoper3
1a Assistant Professor of Medicine, Loyola University Medical Center, Division of Endocrinology and Metabolism, Osteoporosis and Metabolic Bone Disease Center, 2160 S. First Avenue, Bldg 54, Maywood, IL 60153, USA. pcamach@lumc.edu.
Expert Review of Endocrinology & Metabolism
|February 13, 2019
Summary
Recent osteoporosis advances offer new treatment options. This review covers FDA-approved drugs for postmenopausal osteoporosis, including combination therapies and emerging treatments.
Area of Science:
- Endocrinology
- Pharmacology
- Geriatrics
Background:
- Osteoporosis management has evolved significantly due to recent scientific breakthroughs.
- Postmenopausal osteoporosis remains a critical health concern, necessitating effective therapeutic strategies.
Purpose of the Study:
- To review the safety and efficacy of US FDA-approved medications for postmenopausal osteoporosis.
- To explore various administration strategies, including combination, sequential, and intermittent drug use.
- To provide an overview of novel and promising agents in osteoporosis therapy.
Main Methods:
- Comprehensive literature review of US FDA-approved osteoporosis drugs.
- Analysis of clinical studies focusing on safety, efficacy, and usage patterns.
- Evaluation of emerging therapeutic agents and their potential clinical applications.
Main Results:
- Detailed assessment of established pharmacotherapies for postmenopausal osteoporosis.
- Evidence supporting the benefits and risks of combined, sequential, and intermittent drug regimens.
- Identification of promising investigational agents for future osteoporosis treatment.
Conclusions:
- Current FDA-approved drugs offer effective options for osteoporosis prevention and treatment.
- Combination and alternative dosing strategies may enhance therapeutic outcomes.
- Ongoing research into novel agents holds promise for advancing osteoporosis care.
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