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Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
Published on: February 7, 2021
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Hydrogels and Their Applications in Targeted Drug Delivery
Radhika Narayanaswamy1, Vladimir P Torchilin2
1Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, MA 02115, USA. narayanaswamy.r@husky.neu.edu.
Molecules (Basel, Switzerland)
|February 13, 2019
Summary
Hydrogels offer advanced drug delivery, minimizing toxicity and improving therapeutic outcomes. Their tunable properties enable controlled release and protection for various applications, including cancer and diabetes treatment.
Area of Science:
- Biomaterials Science
- Drug Delivery Systems
- Polymer Chemistry
Background:
- Conventional drug delivery faces challenges like systemic toxicity and frequent dosing.
- Hydrogels present a promising alternative due to their biocompatibility and tunable properties.
Purpose of the Study:
- To explore the potential of hydrogels for targeted drug delivery.
- To highlight advancements and modifications of hydrogels for optimized therapeutic benefits.
Main Methods:
- Review of literature on hydrogel properties and applications in drug delivery.
- Discussion of hydrogel characteristics, including porosity and water content.
- Analysis of modifications for targeted delivery and therapeutic efficacy.
Main Results:
- Hydrogels demonstrate excellent controlled drug release capabilities.
- They offer protection for labile drugs and minimize systemic toxicity.
- Hydrogels show versatility in applications beyond drug delivery, such as wound dressings and tissue engineering.
Conclusions:
- Hydrogels are highly adaptable and efficient drug delivery systems.
- Their properties can be tailored for targeted delivery in diseases like cancer and diabetes.
- Hydrogels represent a significant advancement in developing effective therapeutic strategies.
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