Related Experiment Video
Updated: Jan 29, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Antegrade thoracic endovascular aneurysm repair via the ascending aorta
Kosuke Fujii1, Toshihiko Saga1, Masahiko Onoe1
1Department of Cardiovascular Surgery, Faculty of Medicine, Kindai University, Osaka, Japan.
Purpose:
We performed antegrade thoracic endovascular aneurysm repair via the ascending aorta in selected high-risk patients scheduled for open surgery, in whom an iliofemoral or abdominal aortic approach was not feasible. We present our initial experience with this approach.
Methods:
Of 16 consecutive patients who underwent antegrade endovascular aneurysm repair via the ascending aorta at our institution, 3 had an emergency intervention for rupture and 3 had an urgent intervention for impending rupture or complicated aortic dissection. The procedure was scheduled in 10 patients. The median patient age was 77 years. In 13 patients, one or more concomitant procedures were performed. In 6 patients, vascular access for endovascular aneurysm repair was obtained via a branch of the replacement graft. In 10 patients, direct cannulation of the ascending aorta was carried out using 2 pursestring sutures.
Results:
The initial success rate was 100%. Early mortality occurred in 2 (12.5%) patients because of multiple organ failure in one and heart failure in the other. No patient required a second intervention during follow-up. The mean duration of follow-up was 19 months.
Conclusion:
The antegrade approach is a useful alternative in patients with no access suitable for endovascular aneurysm repair and who are not appropriate candidates for open conventional thoracic aortic surgery. This approach is applicable to selected patients.
Related Concept Videos
Thoracic Aorta
The Aorta
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...
Mismatch Repair
The Arch of Aorta
Encircling the heart, the coronary arteries form a ring-like structure before...
Overview of DNA Repair
Chemically...
Base Excision Repair
The first step of...

