Related Experiment Video
Updated: Jan 29, 2026

Examining Changes in HRV and Emotion Following Artmaking with Three Different Art Materials
Published on: January 11, 2020
Cardiac Surgery in HIV Patients: State of the Art
Bobby Yanagawa1, Subodh Verma1, Girish Dwivedi2
1Division of Cardiac Surgery, St Michael's Hospital, Toronto, Ontario, Canada.
Insights
Antiretroviral therapy allows HIV patients to live longer, increasing risks of heart disease. Cardiac surgery outcomes are improving for these patients, necessitating specialized care and safety protocols.
Area of Science:
- Cardiology
- Infectious Diseases
- Surgical Outcomes
Background:
- Combined antiretroviral therapy has transformed HIV management, leading to increased longevity.
- HIV-positive patients now face chronic illnesses, including cardiovascular diseases, as potential treatment side effects.
- Cardiovascular diseases are a significant cause of illness and death in individuals with HIV.
Purpose of the Study:
- To provide an overview of current cardiac surgery outcomes in HIV-positive patients.
- To discuss ethical considerations in the surgical care of this population.
- To outline strategies for protecting surgical teams from HIV transmission.
Main Methods:
- Review of contemporary outcomes of cardiac surgery in HIV-positive patients.
- Examination of ethical issues in patient selection and surgical management.
- Discussion of safety protocols for healthcare professionals.
Main Results:
- A shift towards conventional and durable surgical therapies in HIV-positive patients.
- Improved understanding of cardiac surgery outcomes in this complex group.
- Identification of necessary safety measures for surgical teams.
Conclusions:
- HIV-positive patients are increasingly candidates for diverse cardiac surgical interventions.
- Comprehensive care requires a multidisciplinary heart team approach involving infectious disease specialists.
- Ethical considerations and team protection are crucial for successful surgical outcomes.
Abstract:
The clinical status of HIV infection has changed dramatically with the introduction of combined antiretroviral therapy. Patients with HIV are now living long enough to be susceptible to chronic illnesses, such as coronary disease and nonischemic cardiomyopathy, which can be consequences of the combined antiretroviral therapy treatment itself. Cardiovascular diseases are a major source of morbidity and mortality in HIV-positive patients. Increasingly, such patients might be candidates for the full range of cardiac surgical interventions, including coronary bypass, valve surgery, and heart transplantation. There has been a shift from offering palliative procedures such as pericardial window and balloon valvuloplasty, to more conventional and durable surgical therapies in HIV-positive patients. We herein provide an overview of the contemporary outcomes of cardiac surgery in this complex and unique patient population. We review some of the ethical issues around the selection and surgical care of HIV-positive patients. We also discuss strategies to best protect the surgical treatment team from the risks of HIV transmission. Finally, we highlight the need for involvement of dedicated infectious disease professionals in a multidisciplinary heart team approach, aiming at the comprehensive care of these unique and complex patients.
More Related Videos
Related Concept Videos
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
The Cardiac Cycle
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and...
Cardiac Cycle
During the cardiac cycle, blood flow through the heart is regulated entirely by changing pressure gradients. This sequence of events begins with the heart in a state of total relaxation, known as mid-to-late diastole, during which blood passively flows from...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...

