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Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr)

Laura Ramirez Aguilar1, Juliana Acosta-Uribe2, Margarita M Giraldo1

  • 1Grupo de Neurociencias de Antioquia, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|February 13, 2019
PubMed
Abstract

Keywords:
Admixture in Latin AmericaAutosomal dominant Alzheimer's diseaseFounder effectGenetic BottleneckGenetic driftPhenotype genotype correlationPresenilin 1

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