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Causes of secondary hypertension from a single center in Northern Greece; a retrospective clinical study

Theodoros Michailidis1, Dimitrios Patoulias2, Michalis Charalampidis3

  • 1Department of Internal Medicine, General Hospital of Veria, Veria, Greece.

Folia Medica Cracoviensia
|February 13, 2019
PubMed

Insights

Secondary hypertension affects 7.8% of patients, with common causes including medication and sleep disorders. Thorough diagnostic work-ups are crucial for identifying underlying conditions and initiating targeted hypertension treatment.

Area of Science:

  • Cardiology
  • Endocrinology
  • Nephrology

Background:

  • Hypertension is a prevalent condition, with idiopathic hypertension being most common.
  • Secondary hypertension, caused by identifiable underlying conditions, is often underestimated.
  • Identifying secondary hypertension is critical for effective patient management.

Purpose of the Study:

  • To determine the frequency and causes of secondary hypertension in a Greek outpatient population.
  • To highlight the importance of a comprehensive diagnostic approach for hypertensive patients.

Main Methods:

  • Retrospective study of 447 hypertensive patients aged 20-84 years.
  • Systematic evaluation for secondary causes of hypertension.
  • Analysis of identified causes and their prevalence.

Main Results:

  • 35 out of 447 subjects (7.8%) were diagnosed with secondary hypertension.
  • Most frequent causes included glucocorticoid intake (14 cases), obesity hypoventilation syndrome (6 cases), and obstructive sleep apnea (2 cases).
  • Preeclampsia was identified in 2 cases.

Conclusions:

  • A significant proportion of hypertensive patients have an underlying, treatable cause.
  • Comprehensive diagnostic evaluation is essential for accurate diagnosis and targeted treatment of hypertension.
  • Findings align with previous reports on secondary hypertension prevalence in Greece.

Keywords:
biomarkerdiagnosisprevalencesecondary hypertension

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