Related Experiment Video
Updated: Jan 29, 2026

Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Efficacy of Surgical Excision for Nevus Sebaceous - Vietnamese Experience
Thuong Nguyen Van1,2, Hien Le Thanh1, Tan Nguyen Manh1
1National Hospital of Dermatology and Venereology, Hanoi, Vietnam.
Background:
Nevus Sebaceous (NS) is hamartoma predominantly composed of sebaceous glands and is classified as a type of epidermal nevus. In most case, clinical manifestation of NS is typical, so histopathology examination is important only in atypical lesions for its risk of malignancy. Clinical symptoms are plaques or papules (100%), appearing in the head area (100%) with smooth surface (65.8%), usually with hair loss (60.7%). The histopathology is mostly characterized by the image of sebaceous gland hyperplasia (100%), no hair follicles (60.7%) or immature follicles (14.3%).
Aim:
The aim of our study is describing clinical and histopathological manifestation, make diagnosis and evaluate the best therapy.
Methods:
Our study recruited 38 patients with NS, 3 patients (7.9%) with atypical aspects. All patients were treated by surgical excision.
Results:
Complications as hair loss and infections were reported in 36.8% patients. No patients had recurrence after one year of treatment.
Conclusion:
Based upon our experience, surgery is cheap, simple, associated with high aesthetics effectiveness and low recurrence rate, proposing as the first choice for treatment of NS.
Related Concept Videos
Base Excision Repair
The first step of...
Base Excision Repair
Nucleotide Excision Repair
Nucleotide Excision Repair
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
Accessory Structures of the Skin: Sebaceous Glands
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Self-Efficacy

