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A Micropatterning Assay for Measuring Cell Chirality
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Chiral Sulfoxide Ligands in Asymmetric Catalysis
Tao Jia1,2, Min Wang1,2, Jian Liao3,4
1Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China.
Topics in Current Chemistry (Cham)
|February 13, 2019
Summary
Chiral sulfoxides are versatile ligands for transition metal asymmetric catalysis. This review documents their properties, design, and applications in various asymmetric catalytic reactions since 1976.
Area of Science:
- Organic Chemistry
- Catalysis
- Asymmetric Synthesis
Background:
- The use of chiral sulfoxides as ligands in transition metal catalysis was first explored in 1976.
- Significant research has since focused on their properties, design, and applications.
Purpose of the Study:
- To comprehensively document the existing literature on chiral sulfoxide ligands.
- To highlight their role in various asymmetric catalytic reactions.
Main Methods:
- Literature review and synthesis of existing studies.
- Analysis of reported properties, design strategies, and applications of chiral sulfoxide ligands.
Main Results:
- Chiral sulfoxides have been extensively studied and applied in asymmetric catalysis.
- A wide range of asymmetric transformations utilize these ligands.
Conclusions:
- Chiral sulfoxide ligands are crucial in advancing asymmetric catalysis.
- Continued research in this area promises further developments in enantioselective synthesis.
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