Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

19.4K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.4K
Anatomical Movements00:51

Anatomical Movements

15.6K
Anatomical movements refer to the various actions or motions that can be performed by the body's joints and muscles. These movements are described using specific terms to provide a standardized way of discussing and understanding the range of motion at different joints.
Here are some common anatomical movements:
Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist,...
15.6K
The Movement of Organelles and Vesicles01:43

The Movement of Organelles and Vesicles

6.4K
In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These filaments serve as tracks for transporting cellular cargo. Specialized motor proteins use the chemical energy stored in adenosine triphosphate (ATP) for this transport. During interphase, microtubules are polarized, with the plus-end towards the cell periphery and the minus-end towards the cell center. Two microtubule-associated motor proteins,...
6.4K
Fluid Movement Between Compartments01:18

Fluid Movement Between Compartments

4.0K
The force applied by fluids against a surface, known as hydrostatic pressure, initiates the transfer of fluid among different compartments. Within our blood vessels, the blood's hydrostatic pressure is a result of the heart's pumping action. At the arteriolar end of capillaries, hydrostatic pressure (capillary blood pressure) exceeds the opposing colloid osmotic pressure created primarily by plasma proteins like albumin. This discrepancy in pressure propels plasma and nutrients from the...
4.0K
Movement Joints in Buildings01:27

Movement Joints in Buildings

345
Movement joints in buildings are essential design elements that accommodate inevitable motions caused by various factors such as temperature changes, moisture content variations, and structural deflections. These motions, if not considered in design and construction, can lead to unsightly or dangerous damage. Movement joints are incorporated in different forms to manage these stresses and allow materials to move without causing distress.
The simplest type of movement joints, working joints, are...
345
Intracellular Movement of Viruses and Bacteria01:10

Intracellular Movement of Viruses and Bacteria

3.5K
Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a...
3.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Céline Dion Effect: high-profile public announcements and the epidemiology of stiff-person syndrome.

Journal of neurology·2026
Same author

Falls in Functional Neurological Disorder: Prevalence, Risk Factors and Clinical Implications.

European journal of neurology·2026
Same author

Functional neurological symptoms occur commonly in healthy adults: implications for the pathophysiology of FND.

CNS spectrums·2026
Same author

Comorbidities and Outcomes in People With Functional Neurological Disorder.

JAMA neurology·2026
Same author

Aetiological factors in functional seizures and functional motor symptoms: shared and distinct features.

Journal of neurology, neurosurgery, and psychiatry·2026
Same author

The journey to diagnosis and care of functional neurological disorder (FND).

PloS one·2026
Same journal

The Noradrenergic Brain in Parkinson's Disease.

Current neurology and neuroscience reports·2026
Same journal

Mapping the Silent Onset of Parkinson's Disease: Monoamine Imaging in the Era of the Race for Preclinical Intervention.

Current neurology and neuroscience reports·2026
Same journal

Functional and Structural Brain Imaging Correlates of Treatment Response in Functional Movement Disorder.

Current neurology and neuroscience reports·2026
Same journal

Astrocytopathy in Wernicke Encephalopathy and Neuromyelitis Optica Spectrum Disorder. Pathogenic Differences With Occasional Clinical and Neuroimaging Overlap. A Review.

Current neurology and neuroscience reports·2026
Same journal

When is the Radiologically Isolated Syndrome already Multiple Sclerosis According to the 2024 McDonald Criteria?

Current neurology and neuroscience reports·2026
Same journal

Assessment and Management of Post-traumatic Headache.

Current neurology and neuroscience reports·2026
See all related articles

Related Experiment Video

Updated: Jan 29, 2026

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa
08:10

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa

Published on: February 2, 2018

15.5K

Neuroimaging in Functional Movement Disorders.

Jacob J Roelofs1,2, Tiago Teodoro2,3, Mark J Edwards4,5

  • 1Southmead Hospital, North Bristol NHS Trust, Bristol, UK.

Current Neurology and Neuroscience Reports
|February 13, 2019
PubMed
Summary
This summary is machine-generated.

Neuroimaging is revealing the complex brain mechanisms behind functional movement disorders. This research challenges old ideas and supports new neurobiological models of these disabling conditions.

Keywords:
Conversion disorderFunctional movement disordersImagingMRIPsychogenicfMRI

More Related Videos

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
15:18

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Published on: July 30, 2009

18.7K
Basics of Multivariate Analysis in Neuroimaging Data
06:35

Basics of Multivariate Analysis in Neuroimaging Data

Published on: July 24, 2010

17.3K

Related Experiment Videos

Last Updated: Jan 29, 2026

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa
08:10

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa

Published on: February 2, 2018

15.5K
Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
15:18

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Published on: July 30, 2009

18.7K
Basics of Multivariate Analysis in Neuroimaging Data
06:35

Basics of Multivariate Analysis in Neuroimaging Data

Published on: July 24, 2010

17.3K

Area of Science:

  • Neurology
  • Neuroscience
  • Psychiatry

Background:

  • Functional movement disorders (FMDs) are common and disabling conditions characterized by abnormal movement control.
  • Historically, FMDs were often misunderstood, attributed to psychological factors or malingering.
  • Recent shifts in understanding emphasize neurobiological models involving emotional processing, self-representation, and agency.

Purpose of the Study:

  • To review the current evidence on neuroimaging in FMDs.
  • To explore the role of neuroimaging in understanding the pathophysiology of FMDs.

Main Methods:

  • Review of recent scientific literature and neuroimaging studies in FMDs.
  • Analysis of emerging neurobiological theories and their supporting evidence.

Main Results:

  • Neuroimaging provides new insights into FMD pathophysiology.
  • Evidence supports neurobiological models implicating dysfunctional emotional processing, self-image, and agency.
  • Subtle structural brain changes are observed in FMD patients, challenging a strict functional/structural dichotomy.

Conclusions:

  • Neuroimaging is crucial for unraveling the complex pathophysiology of FMDs.
  • Current research supports a move away from purely psychological explanations towards integrated neurobiological models.
  • FMDs involve complex brain alterations, not strictly functional or structural.