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Possible involvement of nuclei in cadmium-induced modifications of cultured cells
M A Fighetti1, M Miele, A Montella
1Institutes of Pharmacology, University of Sassari, Italy.
Archives of Toxicology
|January 1, 1988
Abstract:
Reduced metaphase number and shortening of metaphase chromosomes were detected in McCoy cells exposed to 100 microM CdSO4 (maximal exposure time: 7 h). One hour exposure to 109Cd was enough to label the cell nucleus. This possibly suggests an early nuclear involvement in Cd-induced cell damage.