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Updated: Jan 29, 2026
Tuning the Acidity of Pt/ CNTs Catalysts for Hydrodeoxygenation of Diphenyl Ether
Published on: August 17, 2019
Prevalence of Diarylprolinol Silyl Ethers as Catalysts in Total Synthesis and Patents
Gabriel J Reyes-Rodríguez1, Nomaan M Rezayee1, Andreu Vidal-Albalat1
1Department of Chemistry , Aarhus University , DK-8000 Aarhus C , Denmark.
Abstract:
Diarylprolinol silyl ethers are among the most utilized stereoselective organocatalysts for the construction of complex molecules. With their debut in 2005, these catalysts have been applied in numerous method developments primarily leveraging enamine and iminium-ion catalysis. These strategies have extended into the preparation of complex molecules in both academic and industrial settings. This Review intends to give an overview of the application of the diarylprolinol silyl ether catalysts in total synthesis. Furthermore, integration of these catalysts in patent literature is also disclosed highlighting the versatility of the catalytic system.
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