Related Experiment Videos
Protein-losing enteropathy in systemic lupus erythematosus
S E Edmunds1, V Ganju, B R Beveridge
1Department of General Medicine, Sir Charles Gairdner Hospital, Nedlands, W.A.
Australian and New Zealand Journal of Medicine
|December 1, 1988
Abstract:
Two patients with systemic lupus erythematosus (SLE) presented with anasarca, pleural effusions and severe hypoalbuminema. Both were demonstrated to have protein-losing enteropathy, a rare complication of SLE. Other causes of gastrointestinal protein loss were excluded. There were marked similarities in both cases including circulating ANF with speckled staining, anti-(U1)RNP antibodies and low serum complement levels. Complete remission was achieved in both with prednisolone. Anti-(U1)RNP may be a marker for a subset of SLE in which protein-losing enteropathy is a major manifestation.