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Calcium-activated potassium channels of large unitary conductance
M I Behrens1, C Vergara, R Latorre
1Centro de Estudios Científicos de Santiago, Chile.
Abstract:
The large unitary conductance Ca2+-activated K+ channel is a widely distributed channel in cellular membranes of diverse tissues. This type of channel may serve as a link between membrane excitability and cell metabolism. In this review we discuss some aspects of the gating mechanism, calcium activation and function and modulation of BK channels.