Related Experiment Video
Updated: Sep 1, 2026

08:18
A Model of Chronic Nutrient Infusion in the Rat
Published on: August 14, 2013
Effects of alloxan on orotic acid and glycogen content in various vertebrate species
Abstract:
Alloxan treatment induces a decrease of orotic acid content in various organs of carp, frog, pigeon and rat, parallel to a decrease of liver and muscle glycogen content. Loss of orotic acid and glycogen cannot be prevented by orotic acid and carbamyl phosphate given i.p. Mice, rats and pigeons use up and excrete exogenous orotic acid rapidly, but carps and frogs accumulate it.

