Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exponential Functions with Base e01:30

Exponential Functions with Base e

244
Exponential functions with base e are essential for modeling continuous processes of growth and decay. The constant e, approximately 2.718, naturally arises in systems where change occurs proportionally to the current value. A positive exponent represents continuous growth, while a negative exponent represents continuous decay. These functions are especially useful for describing situations where change happens smoothly over time rather than in discrete steps.One clear example of exponential...
244
Applications of Integration to Probability Density Functions01:27

Applications of Integration to Probability Density Functions

52
Continuous probability distributions are used to model random variables that can take on any real value within a specified range. These variables do not take on isolated or countable values but rather exist on a continuum. For example, the height of an individual can be measured with increasing precision—such as 163.5 or 165.25 centimeters—demonstrating that height is a continuous random variable.The behavior of such variables is described using a probability density function (PDF),...
52
Multi-input and Multi-variable systems01:22

Multi-input and Multi-variable systems

413
Cruise control systems in cars are designed as multi-input systems to maintain a driver's desired speed while compensating for external disturbances such as changes in terrain. The block diagram for a cruise control system typically includes two main inputs: the desired speed set by the driver and any external disturbances, such as the incline of the road. By adjusting the engine throttle, the system maintains the vehicle's speed as close to the desired value as possible.
In the absence of...
413
Receptor-mediated Endocytosis01:39

Receptor-mediated Endocytosis

110.8K
Overview
110.8K
Nonsense-mediated mRNA Decay02:27

Nonsense-mediated mRNA Decay

11.8K
The Upf proteins that carry out nonsense-mediated decay (NMD) are found in all eukaryotic organisms, including humans. Each protein has an individual role, but they need to work in collaboration. Upf1 is an ATP-dependent RNA helicase that unwinds the RNA helix. Because Upf1 can unwind any RNA, Upf2 and Upf3 are required to help Upf1 discriminate between nonsense and normal mRNAs.
Usually, Upf3 binds to an Exon Junction Complex (EJC) at mRNA splice sites. If a ribosome fully translates the mRNA,...
11.8K
Functional Groups02:45

Functional Groups

88.4K
Functional groups are a group of atoms with characteristic properties, which when linked to the carbon skeleton of a molecule, alter the properties of that molecule. For example, the presence of certain functional groups on a molecule will make them hydrophilic, whereas others will make them hydrophobic. These functional groups are an indispensable part of organic chemistry and important components of biological molecules, such as carbohydrates, proteins, lipids, and nucleic acids. Each...
88.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

B7 homolog 3-targeted CAR-T cells secreting EGFR T-cell engagers for improved control of glioblastoma progression.

Molecular biomedicine·2026
Same author

Associations of co-exposure to metals and polycyclic aromatic hydrocarbons with aging biomarkers: insights from epidemiology and network toxicology.

Frontiers in public health·2026
Same author

Corrigendum to "Multifunctional gold nanorods in low-temperature photothermal interactions for combined tumor starvation and RNA interference therapy" [Acta Biomaterialia 159, 2023, 324-337].

Acta biomaterialia·2026
Same author

A macrophage-targeted bivalent saRNA vaccine protects against ocular and cutaneous HSV-1 infection in mice.

Journal of controlled release : official journal of the Controlled Release Society·2026
Same author

Genomic Analysis Reveals Dominance of Human Adenovirus Genotype B114 Among Circulating Strains Historically Identified as B3.

Journal of medical virology·2026
Same author

The impact of competition mechanisms on primary school students' digital game-based mathematics learning.

Acta psychologica·2026
Same journal

Dry powder inhaler selection in COPD: integrating device design, formulation performance, and patient inspiratory capability.

Expert opinion on drug delivery·2026
Same journal

Letter to the Editor: 'saving money but costing lives: the lack of integrated dose counters on pressurised metered dose inhalers'.

Expert opinion on drug delivery·2026
Same journal

Response to letter to the editor: 'Saving money but costing lives: the lack of integrated dose counters on pressurised metered dose inhalers'.

Expert opinion on drug delivery·2026
Same journal

Mechanism-guided metal complex therapeutics for biofilm-driven wound infections and transdermal delivery.

Expert opinion on drug delivery·2026
Same journal

Next-generation strategies for PROTAC formulation: mechanistic insights and advanced formulation technologies.

Expert opinion on drug delivery·2026
Same journal

Drug penetration in solid tumors: influence of drug size and capillary architecture.

Expert opinion on drug delivery·2026
See all related articles

Related Experiment Video

Updated: Jan 29, 2026

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

20.0K

Multi-functional chitosan-based smart hydrogels mediated biomedical application.

Min Mu1,2,3, Xiaoling Li1,2,3, Aiping Tong1,2,3

  • 1a State Key Laboratory of Biotherapy and Cancer Center, West China Hospital , Sichuan University , Chengdu , R. P. China.

Expert Opinion on Drug Delivery
|February 13, 2019
PubMed
Summary
This summary is machine-generated.

Chitosan hydrogels offer versatile drug delivery applications due to their biocompatibility and tunable properties. This review explores advancements in smart chitosan hydrogels for enhanced therapeutic efficacy.

Keywords:
Chitosanbiomedicinecarriernew technologysmart hydrogel

More Related Videos

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
10:18

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Published on: May 17, 2022

6.8K
Generation of Alginate Microspheres for Biomedical Applications
10:33

Generation of Alginate Microspheres for Biomedical Applications

Published on: August 12, 2012

21.8K

Related Experiment Videos

Last Updated: Jan 29, 2026

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

20.0K
Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
10:18

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Published on: May 17, 2022

6.8K
Generation of Alginate Microspheres for Biomedical Applications
10:33

Generation of Alginate Microspheres for Biomedical Applications

Published on: August 12, 2012

21.8K

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Drug Delivery Systems

Background:

  • Chitosan, a natural polysaccharide, is valued in biomedicine for biodegradability, non-toxicity, and affordability.
  • Chitosan hydrogels can be engineered into smart systems capable of controlled cargo release via stimuli-responsive sol-gel transitions.
  • These hydrogels are increasingly combined with therapeutic agents for advanced treatment modalities like gene and chemotherapy.

Purpose of the Study:

  • To review the latest advancements in chitosan-based hydrogel delivery systems.
  • To discuss novel technologies and smart chitosan hydrogels for biomedical applications.
  • To analyze current trends, future prospects, and limitations of chitosan hydrogels as biomaterials.

Main Methods:

  • Literature review of state-of-the-art progress in chitosan hydrogel technology.
  • Analysis of smart hydrogel properties and stimuli-responsive mechanisms.
  • Discussion of therapeutic applications and biomaterial limitations.

Main Results:

  • Chitosan hydrogels demonstrate significant potential as carriers for various therapeutic agents.
  • Smart chitosan hydrogels exhibit tunable phase transitions in response to environmental stimuli (pH, temperature, light).
  • Despite advantages, in vivo limitations necessitate further research for broader clinical application.

Conclusions:

  • Chitosan-based hydrogels are promising for developing advanced drug delivery systems.
  • Further research into improving in vivo properties is crucial for realizing the full therapeutic potential of chitosan hydrogels.
  • The field anticipates continued innovation in smart chitosan hydrogels for diverse biomedical applications.