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Renal replacement therapy in elderly patients.

P Fauchald1, D Albrechtsen, T Leivestad

  • 1Medical Department B, National Hospital, University of Oslo, Norway.

Transplant International : Official Journal of the European Society for Organ Transplantation
|October 1, 1988
PubMed
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Renal replacement therapy outcomes for elderly patients in Norway show transplantation offers better survival rates than dialysis. Grafted patients had significantly higher survival, indicating transplantation is preferred for this population.

Area of Science:

  • Nephrology
  • Geriatric Medicine
  • Transplantation Medicine

Background:

  • Elderly patients represent a growing demographic requiring renal replacement therapy (RRT).
  • Outcomes of RRT in older populations are critical for treatment planning and resource allocation.

Purpose of the Study:

  • To evaluate the results of renal replacement therapy (RRT) in elderly patients in Norway.
  • To compare patient and graft survival between transplantation and long-term dialysis in this demographic.

Main Methods:

  • Retrospective analysis of 368 patients aged 60+ years starting RRT between 1981-1985.
  • Follow-up until February 1987, comparing outcomes for grafted, non-grafted, and dialysis patients.
  • Actuarial survival rates calculated at 6, 12, and 48 months post-RRT initiation.

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Main Results:

  • Grafted patients (n=122) showed 93% 6-month, 87% 12-month, and 62% 48-month survival.
  • Non-grafted patients (n=127) had lower survival: 64% at 6 months, 44% at 12 months, and 7% at 48 months.
  • Long-term dialysis patients (n=119) had 63% 6-month, 48% 12-month, and 13% 48-month survival.

Conclusions:

  • Transplantation demonstrated superior patient survival compared to dialysis in elderly Norwegian RRT patients.
  • Good patient and graft survival rates were observed in the transplanted group.
  • Transplantation is suggested as the preferred treatment modality for most elderly patients requiring RRT.