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Updated: Jan 29, 2026
09:41
An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
Published on: July 15, 2015
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Cellular immunotherapy in multiple myeloma
Manh-Cuong Vo1,2, Thangaraj Jaya Lakshmi1, Sung-Hoon Jung1,2
1Research Center for Cancer Immunotherapy, Chonnam National University Hwasun Hospital, Hwasun, Korea.
The Korean Journal of Internal Medicine
|February 14, 2019
Summary
Cellular immunotherapy, including dendritic cells, natural killer cells, and engineered T-cells, offers a promising new treatment era for multiple myeloma (MM). These innovative therapies are rapidly advancing, showing potential to eradicate MM tumors.
Area of Science:
- Immunology
- Oncology
- Cancer Therapy
Background:
- Multiple myeloma (MM) involves impaired immune cell function, allowing tumor immune evasion, growth, and survival.
- Despite recent treatment advancements, MM remains a significant challenge.
- Cellular immunotherapies are emerging as a powerful new approach.
Purpose of the Study:
- To review recent advancements in cellular immunotherapy for multiple myeloma (MM).
- To discuss the potential and future prospects of these novel treatments.
Main Methods:
- Review of current literature on cellular immunotherapy for MM.
- Analysis of treatment efficacy and mechanisms of action for dendritic cells, natural killer cells, and engineered T-cells.
Main Results:
- Cellular immunotherapy demonstrates significant potential in eradicating MM.
- Dendritic cells, natural killer cells, and genetically engineered T-cells are key players in this therapeutic evolution.
Conclusions:
- Cellular immunotherapy represents a new and rapidly advancing therapeutic era for multiple myeloma.
- These treatments hold great promise for improving patient outcomes and overcoming immune evasion in MM.
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