Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Study of permanent artificial tendon.

D Y Dong1, C Y Sheng

  • 1Trauma Center, Postgraduate College of PLA, Beijing, China.

Biomaterials, Artificial Cells, and Artificial Organs
|January 1, 1988
PubMed
Summary

This study developed a porous silastic tube as an artificial tendon in dogs. The tube successfully prevented tissue adhesion, showing promise for flexor tendon reconstruction.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Strong interlayer coupling in two-dimensional PbSe with high thermoelectric performance.

Journal of physics. Condensed matter : an Institute of Physics journal·2020
Same author

Surprisingly good thermoelectric performance of a black phosphorus/blue phosphorus van der Waals heterostructure.

Physical chemistry chemical physics : PCCP·2020
Same author

High thermoelectric performance of half-Heusler compound BiBaK with intrinsically low lattice thermal conductivity.

Journal of physics. Condensed matter : an Institute of Physics journal·2020
Same author

Tissue lipopolysaccharide-binding protein expression in rats after thermal injury: potential role of TNF-alpha.

Burns : journal of the International Society for Burn Injuries·2004
Same author

Anisodamine restores bowel circulation in burn shock.

Burns : journal of the International Society for Burn Injuries·1997
Same author

Extensive wound excision in the acute shock stage in patients with major burns.

Burns : journal of the International Society for Burn Injuries·1995

Area of Science:

  • Biomaterials Science
  • Orthopedic Surgery
  • Regenerative Medicine

Background:

  • Tendon injuries often require complex reconstructive procedures.
  • Preventing adhesions is crucial for successful tendon healing and function.
  • Existing artificial tendon materials face challenges in biocompatibility and integration.

Purpose of the Study:

  • To develop and evaluate a porous silastic tube as a permanent artificial tendon.
  • To assess the tube's ability to prevent adhesions in a canine model.
  • To investigate the potential of this material for flexor digital tendon reconstruction.

Main Methods:

  • A porous silastic tube was used to cover sutured canine tendons (Peronaeus longus and Tibialis anticus).
  • Specimens were collected at various time points (1 week to 11 months) for analysis.
  • Histological evaluations included light microscopy, transmission electron microscopy, and scanning electron microscopy.

Main Results:

  • Tendon healing was primarily an extrinsic process.
  • The silastic tube effectively formed a pseudosheath, preventing adhesion to surrounding tissues.
  • The material demonstrated feasibility for use in tendon graft reconstruction.

Conclusions:

  • Porous silastic tubes show potential as permanent artificial tendons.
  • The pseudosheath formation is key to preventing adhesions and enabling tendon gliding.
  • Further research is needed to optimize porous diameter and spacing for clinical application.

Related Experiment Videos