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Updated: Jan 29, 2026

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
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Optimization of 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidines to generate a highly selective PI3Kδ inhibitor

Toshihiro Hamajima1, Fumie Takahashi1, Koji Kato1

  • 1Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba, Ibaraki 305-8585, Japan.

Bioorganic & Medicinal Chemistry
|February 14, 2019
PubMed

Keywords:
5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidineIsoform selectivityPI3Kδ inhibitor

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