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Atraumatic Splenic Rupture after Myocardial Infarction.
Muhammad Fahad Arshad1, Nasir Javed1, Syed Monawer Karim1
1Doncaster Royal Infirmary, Doncaster, United Kingdom.
European Journal of Case Reports in Internal Medicine
|February 14, 2019
Summary
Dual antiplatelet therapy can cause spontaneous splenic rupture in healthy spleens, even weeks after treatment initiation. This rare but serious condition requires prompt medical attention.
Area of Science:
- Internal Medicine
- Cardiology
- Hematology
Background:
- Atraumatic splenic rupture is a rare, life-threatening condition.
- Often associated with underlying splenic disease or anticoagulation therapy.
- The role of dual antiplatelet therapy (DAPT) in splenic rupture is often underestimated.
Purpose of the Study:
- To report a case of spontaneous splenic rupture in a patient treated with DAPT.
- To highlight DAPT as a potential cause of atraumatic splenic rupture in a previously normal spleen.
Main Methods:
- Case report of an 80-year-old woman.
- Review of literature regarding drug-induced splenic rupture.
Main Results:
- The patient developed spontaneous splenic rupture four weeks after initiating DAPT.
- No pre-existing splenic pathology was identified.
Conclusions:
- Dual antiplatelet therapy can induce atraumatic splenic rupture in a normal spleen.
- Splenic rupture can occur within weeks of starting DAPT.
- Awareness of this adverse effect is crucial for clinicians.
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