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Syphilis with Charcot arthropathy: A case report.
Menglei Wang1, Rongrong Huang2, Li Wang1
1Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Syphilis, a chronic infection, can affect the skeletal system. This case highlights an unusual presentation of syphilis causing Charcot arthropathy in both ankle joints.
Area of Science:
- Infectious Diseases
- Rheumatology
- Orthopedics
Background:
- Syphilis is a chronic systemic infection with potential for multi-organ involvement.
- Skeletal manifestations of syphilis include osteochondritis, osteoarthritis, periostitis, and osteitis.
- Charcot arthropathy is a rare complication, with significantly decreased incidence in recent decades.
Observation:
- The authors report a rare case of syphilis presenting with Charcot arthropathy.
- The patient exhibited Charcot arthropathy affecting bilateral ankle joints.
- This presentation underscores the diverse and sometimes unusual manifestations of tertiary syphilis.
Findings:
- Syphilis can lead to severe joint destruction, mimicking other arthropathies.
- Charcot arthropathy in the context of syphilis indicates advanced disease.
- Early diagnosis and treatment of syphilis are crucial to prevent such complications.
Implications:
- This case emphasizes the importance of considering syphilis in the differential diagnosis of joint destruction, especially Charcot arthropathy.
- Increased awareness among clinicians is needed to recognize this uncommon syphilitic complication.
- Prompt syphilitic infection treatment can prevent debilitating skeletal sequelae.
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