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Updated: Jan 29, 2026

A Modeling and Simulation Method for Preliminary Design of an Electro-Variable Displacement Pump
Published on: June 1, 2022
Preliminary evaluation of a predictive controller for a rotary blood pump based on pulmonary oxygen gas exchange
Feng Huang1,2, Zhe Gou2, Yang Fu3
11 College of Metrology & Measurement Engineering, China Jiliang University, Hangzhou, China.
Abstract:
Physiological control of rotary blood pumps is becoming increasingly necessary for clinical use. In this study, the mean oxygen partial pressure in the upper airway was first quantitatively evaluated as a control objective for a rotary blood pump. A model-free predictive controller was designed based on this control objective. Then, the quantitative evaluation of the controller was implemented with a rotary blood pump model on a complete cardiovascular model incorporated with airway mechanics and gas exchange models. The results show that the controller maintained a mean oxygen partial pressure at a normal and constant level of 138 mmHg in the left heart failure condition and restored basic haemodynamics of blood circulation. A left ventricular contractility recovery condition was also replicated to assess the response of the controller, and a stable result was obtained. This study indicates the potential use of the oxygen partial pressure index during pulmonary gas exchange when developing a multi-objective physiological controller for rotary blood pumps.
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