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Related Experiment Video

Updated: Jan 29, 2026

Iatrogenic Injury Recapitulated: Electroexcision Technique for Urethral Stricture Modeling in Rats
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[Iatrogenic urethral structures in men].

S V Kotov1,2,3, S V Belomyttsev1,2,3, R I Guspanov1,2,3

  • 1N.I. Pirogov RNRMU of Minzdrav of Russia, Department of Urology and Andrology, Moscow, Russia.

Urologiia (Moscow, Russia : 1999)
|February 15, 2019
PubMed
Summary

Iatrogenic urethral strictures, often from catheterization, are common. Urethroplasty is significantly more effective than direct vision internal urethrotomy for treating these strictures.

Keywords:
DVIUbuccal mucosa graftperineal prostatectomyurethral strictureurethroplasty

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Area of Science:

  • Urology
  • Surgical Innovation
  • Patient Outcomes

Background:

  • Iatrogenic urethral damage is a primary cause of urethral strictures in men globally.
  • This condition necessitates evaluating treatment efficacy and patient outcomes.

Purpose of the Study:

  • To determine the frequency of iatrogenic urethral strictures.
  • To assess the effectiveness of various surgical treatments for these strictures.

Main Methods:

  • Retrospective analysis of 133 patients treated for iatrogenic urethral strictures (2011-2016).
  • Patients were categorized into four groups based on the cause: transurethral interventions, post-catheterization, hypospadias repair, and adenomectomy.
  • Diagnosis and recurrence assessment utilized uroflowmetry, urethrography, and urethrocystoscopy.

Main Results:

  • Transurethral interventions and catheterization were the most common causes.
  • Direct vision internal urethrotomy (DVIU) had an overall effectiveness of 52%, while urethroplasty ranged from 83% to 100%.
  • Specific success rates varied by stricture type and treatment method, with urethroplasty demonstrating superior outcomes in most cases.

Conclusions:

  • Iatrogenic urethral strictures can account for up to 45% of cases in urban populations.
  • Urethroplasty is nearly twice as effective as DVIU for treating iatrogenic urethral strictures when the appropriate surgical method is chosen.
  • Treatment success is dependent on accurate diagnosis and tailored surgical approaches for each stricture subgroup.