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Updated: Jan 29, 2026

Synthesis and Characterization of Functionalized Metal-organic Frameworks
Published on: September 5, 2014
Cluster nuclearity control and modulated hydrothermal synthesis of functionalized Zr12 metal-organic frameworks
Shing Bo Peh1, Youdong Cheng1, Jian Zhang1
1Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, 117585 Singapore. chezhao@nus.edu.sg.
Abstract:
The synthesis of chemically stable metal-organic frameworks (MOFs) in benign solvents is a key step towards their scalable production and commercialization. Extending the modulated hydrothermal (MHT) synthesis approach for zirconium (Zr) MOFs, we herein demonstrate cluster nuclearity control over the secondary building units (SBUs) to target Zr6-based and Zr12-based phases for the Zr terephthalate (Zr-BDC) system. Different functional groups (-NH2, -NO2, -Br, -F4) can be incorporated into Zr12-BDC, providing an avenue to further tune the chemical properties of these promising MOFs.
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