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Published on: April 1, 2013
Synthesis of Dibenzophospholes by Tf2O-Mediated Intramolecular Phospha-Friedel-Crafts-Type Reaction
Kazutoshi Nishimura1, Koji Hirano1, Masahiro Miura1
1Department of Applied Chemistry, Graduate School of Engineering , Osaka University , Suita , Osaka 565-0871 , Japan.
Abstract:
A Tf2O-mediated intramolecular phospha-Friedel-Crafts-type reaction of secondary biarylphosphine oxides has been developed. The reaction is promoted simply by Tf2O to form the corresponding dibenzophospholes under metal-free conditions. The starting substrates are readily available and easy-to-handle phosphine oxides, and the regioselectivity is controlled by the innate electronic nature. Thus, this newly developed protocol can provide concise and complementary approach to the highly π-conjugated dibenzophospholes of potent interest in material chemistry.
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