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The history of Nolvadex
1Imperial Chemical Industries PLC, Macclesfield, Cheshire.
Drug Design and Delivery
|July 1, 1988
Abstract:
The research programme leading to the discovery of Nolvadex (tamoxifen, ICI 46474) (2; R1 = Me, X = Et), the anti-oestrogen used widely in the treatment of breast cancer, is described by the chemist involved in the discovery.