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Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

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Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
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Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
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Related Experiment Video

Updated: Jan 29, 2026

Use of the Protease Fluorescent Detection Kit to Determine Protease Activity
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Pathology-linked protease caught in action

Stefan F Lichtenthaler1, Gökhan Güner2

  • 1German Center for Neurodegenerative Diseases (DZNE), Munich Cluster for Systems Neurology (SyNergy), School of Medicine, Klinikum rechts der Isar, DFG Research Unit FOR 2290 and Institute for Advanced Study, Technical University of Munich, Germany. stefan.lichtenthaler@dzne.de.

Science (New York, N.Y.)
|February 16, 2019
PubMed
Summary

No abstract available in PubMed .

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