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Updated: Jan 29, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Left circumflex artery injury postmitral valve surgery, single center experience
Aysha Husain1, Aly Alsanei1, Mohammed Tahir1
1Heart Center, King Faisal Hospital and Research Center, Riyadh Saudi Arabia.
Abstract:
The left circumflex (LCX) artery is located close to the mitral valve (MV), making it susceptible to injury during MV surgery. We are reporting our experience in the diagnosis and management of this complication. We retrospectively reviewed our surgical and coronary angiography databases for patients with documented LCX artery injury during MV surgery between January 2000 and December 2016. The complication was associated with MV replacement (9/1313, 0.7%) but not MV repair (0/393, 0.0%). Eight patients (88.9%) were female and the mean age was 40.4 ± 14.2 years. There was roughly similar distribution of left and right dominant coronary circulations (5 and 4 patients, respectively). Eight patients (88.9%) had ischemic changes on electrocardiogram and ventricular arrhythmias were documented on six patients (66.7%). Three patients (33.3%) were treated with percutaneous coronary intervention while six patients (66.7%) required redo surgery to graft the LCX artery. The 30-day mortality was high (33.3%). A high index of suspicion is required to diagnose this injury. At the moment, no consensus is available on the optimal treatment strategy. We propose percutaneous approach as the first option to spare the patients from undergoing open-heart surgery for the second time.
Insights
Left circumflex artery injury during mitral valve surgery is a rare but serious complication, primarily occurring after valve replacement. Early diagnosis and intervention, potentially via percutaneous coronary intervention, are crucial for patient outcomes.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Cardiac Anatomy
Background:
- The left circumflex (LCX) artery's proximity to the mitral valve (MV) poses a risk of injury during MV surgery.
- Mitral valve surgery, particularly replacement, has been associated with LCX artery injury.
Purpose of the Study:
- To report the experience in diagnosing and managing left circumflex artery injury following mitral valve surgery.
- To evaluate the incidence, clinical presentation, and treatment outcomes of this complication.
Main Methods:
- Retrospective review of surgical and coronary angiography databases.
- Analysis of patient data from January 2000 to December 2016 for documented LCX artery injury during MV surgery.
Main Results:
- The complication occurred in 0.7% of MV replacement cases (9/1313) but not in MV repair (0/393).
- Most affected patients were female (88.9%) with a mean age of 40.4 years, presenting with ECG ischemic changes and ventricular arrhythmias.
- Treatment included percutaneous coronary intervention (33.3%) or redo surgery (66.7%), with a high 30-day mortality (33.3%).
Conclusions:
- A high index of suspicion is necessary for diagnosing LCX artery injury post-MV surgery.
- Optimal treatment strategy remains debated; percutaneous intervention is proposed as a primary option to avoid repeat open-heart surgery.
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