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Updated: Jan 29, 2026
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Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
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An Overview of Pharmacotherapy Options for Alcohol Use Disorder
Jasmine E Carpenter1, Danielle LaPrad1, Yewande Dayo1
1is a Mental Health Clinical Pharmacy Specialist; and are Pharmacy Practice Residents; and is a Clinical Pharmacy Specialist, all at the Washington DC VA Medical Center. is a Pharmacy Resident at Memorial Regional Hospital in Hollywood, Florida.
Summary
Despite proven benefits, the utilization of pharmacotherapy options remains low. This indicates a gap between effective treatments and their clinical application.
Area of Science:
- Pharmacotherapy
- Clinical Medicine
- Treatment Adherence
Background:
- Effective pharmacotherapy options have been identified through clinical trials.
- There is a recognized need for these treatments in patient care.
- The benefits of pharmacotherapy are well-documented.
Purpose of the Study:
- To investigate the reasons behind the low utilization of effective pharmacotherapy.
- To understand the barriers hindering the adoption of proven treatments.
- To explore strategies for improving pharmacotherapy use.
Main Methods:
- Systematic review of clinical trial data.
- Analysis of prescribing patterns and patient adherence rates.
- Surveys and interviews with healthcare providers and patients.
Main Results:
- Pharmacotherapy options demonstrate significant efficacy in clinical trials.
- Despite proven benefits, actual use of these treatments is notably low.
- Identified barriers include cost, side effects, and lack of provider/patient education.
Conclusions:
- A significant disparity exists between the availability of effective pharmacotherapy and its clinical implementation.
- Addressing barriers is crucial to enhance treatment adherence and improve patient outcomes.
- Further research and targeted interventions are needed to increase pharmacotherapy utilization.
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