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3D printed selectable dilution mixer pumps.

Hua Gong1, Adam T Woolley2, Gregory P Nordin1

  • 1Electrical and Computer Engineering Department, Brigham Young University, Provo, Utah 84602, USA.

Biomicrofluidics
|February 16, 2019
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Summary
This summary is machine-generated.

Researchers developed 3D printed microfluidic devices with integrated pumps and mixers. These compact devices offer precise fluid control and selectable dilution ratios for advanced lab-on-a-chip applications.

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Area of Science:

  • Microfluidics
  • 3D Printing
  • Biotechnology

Background:

  • Traditional microfluidic systems often require complex external connections.
  • Integrating active components like pumps and valves directly onto microfluidic chips remains a challenge.

Purpose of the Study:

  • To demonstrate the fabrication of integrated microfluidic devices using 3D printing.
  • To develop and characterize novel 3D printed pumps and mixers with selectable dilution ratios.

Main Methods:

  • Utilized compact chip-to-chip interconnects for external connections.
  • Designed and 3D printed linear dilution mixer pumps (LDMP) and parallelized dilution mixer pumps (PDMP).
  • Developed a low-cost video method for real-time concentration measurement.

Main Results:

  • Successfully fabricated 3D printed pumps, LDMP, and PDMP with small footprints.
  • Achieved full fluid mixing within 6 mixer periods for both LDMP and PDMP.
  • Demonstrated accurate tracking of designed dilution ratios, with PDMP offering a denser set of dilutions.

Conclusions:

  • 3D printing enables the creation of highly integrated microfluidic devices with active components.
  • The developed LDMP and PDMP offer efficient and precise fluid mixing and dilution control.
  • The novel video-based characterization method provides a low-cost approach for microfluidic analysis.