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Treatment of advanced nonsmall cell lung cancer: First line, maintenance and second line - Indian consensus statement
1Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.
Abstract:
The management of advanced nonsmall cell lung cancer (NSCLC) patients is becoming increasingly complex with the identification of driver mutations/rearrangements and development/availability of appropriate targeted therapies. In 2017, an expert group of medical oncologists with expertise in treating lung cancer used data from published literature and experience to arrive at practical consensus recommendations on treatment of advanced NSCLC for use by the community oncologists. This was published subsequently in the Indian Journal of Cancer with a plan to be updated annually. The present document is an update to the 2017 document.
Insights
Managing advanced nonsmall cell lung cancer (NSCLC) is complex. This document updates 2017 consensus recommendations for community oncologists on targeted therapies for NSCLC based on new data.
Area of Science:
- Oncology
- Medical Sciences
- Cancer Research
Background:
- Advanced nonsmall cell lung cancer (NSCLC) management is increasingly complex.
- Identification of driver mutations/rearrangements necessitates targeted therapies.
Purpose of the Study:
- To provide updated practical consensus recommendations for advanced NSCLC treatment.
- To guide community oncologists in utilizing targeted therapies.
Main Methods:
- Expert group of medical oncologists convened.
- Data from published literature and clinical experience were reviewed.
- Consensus recommendations were formulated.
Main Results:
- The document presents an update to the 2017 consensus recommendations.
- It incorporates recent advancements in targeted therapies for NSCLC.
Conclusions:
- Updated recommendations aim to simplify complex treatment decisions for advanced NSCLC.
- This resource supports community oncologists in patient management.
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