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Status of Measles Elimination in Eleven Countries with High Routine Immunisation Coverage in The WHO African Region
Balcha Masresha1, Richard Luce2, Messeret Shibeshi3
1WHO Regional Office for Africa, Brazzaville, Congo.
Background:
Measles elimination is defined as the absence of endemic measles virus transmission in a defined geographic area for at least 12 months in the presence of a well-performing surveillance system. The WHO framework for verification of measles elimination indicates that the achievement of measles and/or rubella elimination should be verified for individual countries.
Objective:
We identified 11 high performing countries based on their first dose measles vaccination coverage, and looked at their performance across the various programmatic parameters, to see if they are ready to undertake the verification of measles elimination.
Methods:
We identified 11 countries with >90% measles first dose coverage for the most recent 5 years according to the WHO UNICEF estimates of national immunisation coverage. We analysed vaccination coverage and surveillance performance in these countries.
Results:
Algeria, Botswana, Gambia, Mauritius, Rwanda, Seychelles have maintained measles first dose (MCV1) coverage of 95% or more since 2011. In 2015, only Algeria, Cape Verde and Seychelles had coverage of 95% or more for the second dose of measles vaccine (MCV2). Of the 22 supplemental immunisation activities (SIAs) among the 11 countries, only 6 had administrative coverage of less than 95%. Only Rwanda and Lesotho attained the case-based surveillance performance targets in all the five years.
Conclusion:
Despite their high routine first dose measles immunisation coverage, all of the 11 countries have some program gaps indicating that they do not meet all the criteria to undergo verification of elimination at this point. It is recommended for these countries to set up national verification committees as per the WHO framework for verification of measles elimination, in order to initiate the documentation and monitoring of progress, and to address programmatic gaps in the coming years.
Insights
High measles vaccination coverage is essential for elimination. However, 11 countries assessed showed program gaps, indicating they are not yet ready for measles elimination verification. Addressing these gaps is crucial for future success.
Area of Science:
- Public Health
- Epidemiology
- Vaccinology
Background:
- Measles elimination requires sustained absence of endemic transmission and robust surveillance.
- The World Health Organization (WHO) mandates country-level verification for measles and rubella elimination.
- High vaccination coverage is a prerequisite for achieving and verifying measles elimination.
Purpose of the Study:
- To evaluate the readiness of 11 high-performing countries for measles elimination verification.
- To assess programmatic parameters beyond first-dose measles vaccination coverage.
- To identify specific gaps hindering the verification process.
Main Methods:
- Identified 11 countries with over 90% measles-first-dose (MCV1) coverage for five years (WHO-UNICEF estimates).
- Analyzed MCV1 and second-dose (MCV2) vaccination coverage rates.
- Assessed performance in supplemental immunization activities (SIAs) and case-based surveillance.
Main Results:
- Six countries (Algeria, Botswana, Gambia, Mauritius, Rwanda, Seychelles) maintained MCV1 coverage >=95% since 2011.
- In 2015, only three countries achieved >=95% MCV2 coverage.
- Supplemental immunization activities showed variable success, with only 6 of 22 activities achieving <95% coverage.
- Only Rwanda and Lesotho met all surveillance targets for five consecutive years.
Conclusions:
- Despite high routine MCV1 coverage, all 11 countries exhibit programmatic gaps preventing immediate measles elimination verification.
- Establishing national verification committees is recommended to document progress and address identified gaps.
- Continued efforts are needed to strengthen immunization programs and surveillance systems for eventual verification.
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