Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ionization Energy

Ionization Energy

The amount of energy required to remove the most loosely bound electron from a gaseous atom in its ground state is called its first ionization energy (IE1). The first ionization energy for an element, X, is the energy required to form a cation with 1+ charge:

Matrix-Assisted Laser Desorption Ionization (MALDI)

Matrix-Assisted Laser Desorption Ionization (MALDI)

Matrix-assisted laser desorption ionization (MALDI) is a powerful analytical technique used in mass spectrometry. It enables the identification and characterization of various biomolecules, including proteins, peptides, nucleic acids, and carbohydrates. MALDI is an ionization technique, widely employed in biological and medical research, as well as in fields like pharmacology and biochemistry.The analyte of interest, a biomolecule or a mixture of biomolecules, is mixed with a suitable matrix...

Harmonic Mean

Harmonic Mean

The arithmetic mean is usually skewed towards the larger values in the data set. Therefore, to avoid this inherent bias towards smaller values, the harmonic mean is used.
Take the example of the speed of a car, which is the measure of the rate of distance traveled. If the vehicle traverses the same distance back-and-forth, its average speed equals the total distance traveled divided by the total time taken. However, if the car moves with varying speeds, then the arithmetic mean is more skewed...

Pulse

Pulse

When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...

Pulse

Pulse

The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...

Simple Harmonic Motion

Simple Harmonic Motion

Simple harmonic motion is the name given to oscillatory motion for a system where the net force can be described by Hooke's law. If the net force can be described by Hooke's law and there is no damping (by friction or other non-conservative forces), then a simple harmonic oscillator will oscillate with equal displacement on either side of the equilibrium position. To derive an equation for period and frequency, the equation of motion is used. The period of a simple harmonic oscillator is given...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Lactate-Modified Prognostic Nutritional Index (LPNI) and Its Association with ICU Mortality in Patients with Sepsis: A Retrospective Cohort Study.

Journal of inflammation research·2026

Same author

Matrix-free, color-tunable carbon quantum dots with solid-state emission for white LEDs.

Discover nano·2026

Same author

Curcumin inhibits the proliferation of diffuse large B-cell lymphoma by inducing ferroptosis via the ACSL4-SAT1-GPX4 axis.

Translational cancer research·2026

Same author

FeP/NiCoP Nanowire Arrays with an Optimized Coordination Environment for Electrocatalytic Water Splitting.

Inorganic chemistry·2026

Same author

Comparative Analysis of ICC and WHO Classifications Reveals Molecular and Clinical Convergence Between AML-MR and MDS/AML.

Hematological oncology·2026

Same author

SPP1 as a central mediator in the tumor microenvironment: Orchestrating cellular crosstalk, immune evasion, and therapy resistance.

Biochimica et biophysica acta. Reviews on cancer·2026

Search research articles

Related Experiment Video

Updated: Jan 29, 2026

Investigation of Early Plasma Evolution Induced by Ultrashort Laser Pulses

Investigation of Early Plasma Evolution Induced by Ultrashort Laser Pulses

Published on: July 2, 2012

Brunel harmonics generated from ionizing clusters by few-cycle laser pulses.

Xiaohui Gao, Bonggu Shim, Michael C Downer

|February 16, 2019

Summary

This summary is machine-generated.

We theoretically investigate harmonic generation in nano-clusters using intense laser pulses. A Brunel-type mechanism, driven by subcycle ionization, shifts spectra toward odd harmonics, suggesting potential for vacuum-ultraviolet radiation sources.

More Related Videos

Analysis of Complex Molecules and Their Reactions on Surfaces by Means of Cluster-Induced Desorption/Ionization Mass Spectrometry

Analysis of Complex Molecules and Their Reactions on Surfaces by Means of Cluster-Induced Desorption/Ionization Mass Spectrometry

Published on: March 1, 2020

Spatial Separation of Molecular Conformers and Clusters

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

Related Experiment Videos

Last Updated: Jan 29, 2026

Investigation of Early Plasma Evolution Induced by Ultrashort Laser Pulses

Investigation of Early Plasma Evolution Induced by Ultrashort Laser Pulses

Published on: July 2, 2012

Analysis of Complex Molecules and Their Reactions on Surfaces by Means of Cluster-Induced Desorption/Ionization Mass Spectrometry

Analysis of Complex Molecules and Their Reactions on Surfaces by Means of Cluster-Induced Desorption/Ionization Mass Spectrometry

Published on: March 1, 2020

Spatial Separation of Molecular Conformers and Clusters

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

Area of Science:

Plasma Physics
Nonlinear Optics
Atomic and Molecular Physics

Background:

Harmonic generation is a key process in nonlinear optics, used for frequency conversion.
Ionizing nano-clusters with intense lasers presents unique dynamics compared to atomic gases.
Few-cycle laser pulses enable exploration of ultrafast ionization phenomena.

Purpose of the Study:

To theoretically investigate harmonic generation from ionizing nano-clusters irradiated by intense few-cycle laser pulses.
To identify the underlying harmonic generation mechanism and its characteristics.
To assess the potential of nano-clusters as a source for vacuum-ultraviolet (VUV) radiation.

Main Methods:

Theoretical study of harmonic generation.
Analysis of subcycle ionization dynamics in nano-clusters.
Modeling of Mie oscillations and their influence on harmonic spectra.

Main Results:

Identification of a Brunel-type harmonic generation mechanism originating from subcycle ionization.
Observation of spectral shifts toward odd-order harmonics of the Mie frequency (ωM) due to efficient Mie oscillations.
Significant single-cluster harmonic yield and relaxed phase-matching conditions in overdense clustered plasmas.

Conclusions:

Few-cycle laser pulse irradiation of nano-clusters drives a unique harmonic generation mechanism.
Nano-clusters can efficiently generate odd-order harmonics of the Mie frequency.
Ionizing nano-clusters offer a promising avenue for generating vacuum-ultraviolet radiation.