Consistent Iodine Status Assessment in Chinese Adults by Different Spot Urinary Iodine Concentrations in a Day
Wendi Liu1, Peng Zhang1, Xin Zhao2
1Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University , Tianjin , China.
Abstract:
Objective: The aim of this research was to determine the correction coefficients of different spot urinary iodine concentrations (UICs) in a day to predict the early morning UIC, to make the different spot UICs of a day comparable in assessing iodine status in the same population. Methods: In total, 424 participants aged 18 to 28 years were recruited from Tianjin, China. Three spot urine samples were collected from each participant during three periods of the day (6:30-7:00, 10:00-10:30, and 16:00-16:30). A total of 1272 urine samples were collected. A 24-hour dietary record was reported by each participant for 3 consecutive days. Results: Both the UICs at 10:00-10:30 and 16:00-16:30 were higher than that at 6:30-7:00 (181.75 or 198.15μg/L vs 157.69 μg/L; all p < 0.05). Bland-Altman plot showed no good agreements between the other two spot UICs and that at 6:30-7:00 with both Bland-Altman indexes of 7.1%. Correction coefficients used to predict UIC at 6:30-7:00 from the UIC at 10:00-10:30 and 16:00-16:30 were 0.9231 and 0.8592, respectively. The predicted UICs at 6:30-7:00 by using the UIC at 10:00-10:30 and 16:00-16:30 both had no statistically significant difference with the actual UIC at 6:30-7:00 (all p > 0.05). Bland-Altman plot showed good agreements between the predicted UICs and actual UICs at 6:30-7:00 with both Bland-Altman indexes of 4.5%. Conclusions: It was reliable to predict the early morning UIC using correction coefficients of other spot UIC of the day, which gave a new idea for standardizing the methodology of surveys assessing iodine status of a population.
More Related Videos
05:32Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
Published on: September 21, 2015
10:19Solution-Processed "Silver-Bismuth-Iodine" Ternary Thin Films for Lead-Free Photovoltaic Absorbers
Published on: September 27, 2018
Related Concept Videos
Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene
Expressing Solution Concentration
Concentrations may be quantitatively assessed using a wide variety of measurement units, each convenient for particular applications. Molarity (M) is a useful concentration unit for many applications in chemistry.
Coefficient of Variation
The coefficient of variation is a practical statistical tool in finance. It allows investors to assess the volatility or...
Distance Corrections
Coefficient of Correlation
If you suspect a linear relationship between x and y, then r can measure how strong the linear relationship is.
What the VALUE of r tells us:
The value of r is always between –1 and +1: –1 ≤ r ≤ 1.
The size of the correlation r indicates the...
Confidence Coefficient
