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Design and Synthesis of a Novel Banana-Shaped Functional Molecule via Double Cross-Coupling
Bingchuan Yang1,2,3, Guodong Shen4, Xianqiang Huang5
1School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252000, China. bingchuan@mail.usf.edu.
Abstract:
A novel banana-shaped molecule using 2,8-Dimethyl-6H,12H-5,11-methanodibenzo [b,f] [1,5]diazocine (Tröger's base) as bent-core was synthesized via double Carbon-Carbon cross-coupling reaction. The double Sonogashira cross-coupling reaction was optimized by using Pd(PPh₃)₂Cl₂ as catalyst, CuI as cocatalyst and diisopropylamine as base in place of triethylamine. The structure of this compound was confirmed by ¹H-NMR, 13C-NMR, Fourier transform infrared (FT-IR) spectroscopy and mass spectrometry.
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