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Expired Tidal Volume Variation in Extremely Low Birth Weight and Very Low Birth Weight Infants on Volume-Targeted

Samuel Wong1, Honglang Wang2, Robert Tepper3

  • 1Section of Neonatology, Indiana University, Indianapolis, Indiana.

The Journal of Pediatrics
|February 17, 2019
PubMed

Insights

Volume-targeted ventilation (VTV) ensured consistent small tidal volume delivery for extremely low birth weight (ELBW) and very low birth weight (VLBW) infants. This method proved effective regardless of infant size or set volume.

Area of Science:

  • Neonatal medicine
  • Pediatric respiratory care
  • Critical care for newborns

Background:

  • Extremely low birth weight (ELBW) and very low birth weight (VLBW) infants often require mechanical ventilation.
  • Precise control of tidal volumes is crucial to minimize lung injury in vulnerable neonates.
  • Existing ventilation methods may struggle to deliver consistent tidal volumes in this population.

Purpose of the Study:

  • To evaluate the efficacy of volume-targeted ventilation (VTV) in delivering precise tidal volumes to ELBW and VLBW infants.
  • To assess the consistency of tidal volume delivery irrespective of infant characteristics or ventilator settings.

Main Methods:

  • A prospective study was conducted involving ELBW and VLBW infants.
  • Volume-targeted ventilation (VTV) mode was utilized for respiratory support.
  • Tidal volume delivery was monitored and analyzed.

Main Results:

  • VTV demonstrated consistent tidal volume delivery in both ELBW and VLBW infant groups.
  • Delivery consistency was maintained independently of infant's gestational age.
  • Tidal volume delivery remained consistent regardless of birth weight or the targeted volume setting.

Conclusions:

  • Volume-targeted ventilation (VTV) is an effective mode for precise respiratory support in ELBW and VLBW infants.
  • VTV offers reliable tidal volume delivery, potentially reducing ventilator-induced lung injury.
  • This ventilation strategy provides consistent respiratory care for the most vulnerable neonates.

Keywords:
extremely low birth weightmechanical ventilationneonateprematurevery low birth weightvolume-targetedvolutrauma

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