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Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo
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Stereotaxic Targeting of Alpha-Synuclein Pathology in Mouse Brain Using Preformed Fibrils

Bin Zhang1, Victoria Kehm1, Ron Gathagan1

  • 1Center for Neurodegenerative Disease Research, Institute on Aging, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

Methods in Molecular Biology (Clifton, N.J.)
|February 17, 2019
PubMed

Keywords:
MicroinjectionStereotaxicTransmission studyin vivo modelα-Synucleinα-Synuclein preformed fibrils (PFFs)

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