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Updated: Jan 29, 2026

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Association between Mapuche Ethnicity and Stroke: A Case-Control Study.

Álvaro Soto1, Gladys Morales2, Rosa Provoste3

  • 1Department of Medical Specialties, Faculty of Medicine, Universidad de La Frontera, Temuco, Chile; Unit of Neurology, Dr. Hernán Henríquez Aravena Hospital, Temuco, Chile; Center for Research in Cardiovascular and Nutritional Epidemiology (EPICYN), Universidad de La Frontera, Temuco, Chile.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|February 18, 2019
PubMed
Summary

This study found no significant link between Mapuche ethnicity and stroke incidence in the Araucanía Region. Further research is needed to understand stroke risk factors in diverse populations.

Keywords:
Strokecase-control studiesethnic groupsrisk factors

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Area of Science:

  • Public Health
  • Epidemiology
  • Medical Research

Background:

  • Native populations and minorities experience higher stroke incidence.
  • The Araucanía Region has a significant indigenous population (34%).
  • The relationship between Mapuche ethnicity and stroke is not well-understood.

Purpose of the Study:

  • To investigate the association between Mapuche ethnicity and stroke occurrence.
  • To estimate the magnitude of this association in patients admitted to Dr. Hernán Henríquez Aravena Hospital (HHHA).

Main Methods:

  • Incident case-control-paired study design.
  • 104 stroke cases and matched controls (gender, age ±5 years) from HHHA.
  • Conditional logistic regression analysis.

Main Results:

  • Mapuche ethnicity proportion was similar in cases (27.9%) and controls (32.7%).
  • Hypertension and overweight-obesity were associated with stroke.
  • Mapuche ethnicity was not statistically associated with stroke (OR=.75, P=.47).

Conclusions:

  • No statistically significant evidence supports an association between Mapuche ethnicity and stroke.
  • Control variables did not alter the non-significant effect of ethnicity on stroke.