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Updated: Jan 29, 2026

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Published on: January 18, 2018
Current treatment and management of infantile hemangiomas
Kellie R Satterfield1, Christopher B Chambers2
1Department of Medicine, Scripps Mercy Hospital, San Diego, California, USA; Department of Ophthalmology, University of Washington, Seattle, Washington DC, USA.
Insights
Infantile hemangiomas are common benign vascular tumors in children. While often resolving spontaneously, severe cases require treatment, with beta-blockers being a primary option.
Area of Science:
- Pediatric Dermatology
- Vascular Biology
- Oncology
Background:
- Infantile hemangiomas are common benign vascular tumors in children.
- They typically involute spontaneously but can cause significant cosmetic or functional issues.
- Life-threatening complications are rare but possible depending on location and size.
Purpose of the Study:
- To review current management strategies for infantile hemangiomas.
- To discuss the benefits and risks of various treatment modalities.
- To provide an overview of therapeutic options for infantile capillary hemangiomas.
Main Methods:
- Literature review of infantile hemangioma treatments.
- Analysis of previously reported therapeutic modalities.
- Discussion of current recommended management.
Main Results:
- Beta-blockers are a mainstay therapy due to efficacy and safety.
- Other treatments include corticosteroids, imiquimod, vincristine, bleomycin A5, interferon α, captopril, laser therapy, and surgery.
- Treatment choice depends on hemangioma characteristics and potential complications.
Conclusions:
- Infantile hemangiomas require careful management based on individual patient factors.
- A range of treatment options exist, each with specific benefits and risks.
- Timely intervention can prevent long-term sequelae and improve outcomes.
Abstract:
Infantile hemangiomas, otherwise known as infantile capillary hemangiomas, strawberry hemangiomas, or strawberry nevi, are nonmalignant vascular tumors that commonly affect children. The natural disease course typically involves growth for up to a year, followed by regression without treatment over a period of years with no cosmetic or functional sequelae. Less commonly, however, infantile hemangiomas can become a threat to vision or even life depending on location and size of the lesion. In addition, infantile hemangiomas, particularly those involving the face, may be disfiguring and result in lifelong sequelae. β-blockers have become a mainstay of therapy given their relatively low-risk profile and efficacy. Other treatment modalities previously described in the literature include corticosteroids (both intralesional and systemic), imiquimod, vincristine, bleomycin A5, and interferon α. More recently, angiotensin-converting enzyme inhibitors such as captopril have been used. Laser therapy and, less commonly, surgical excision are also available treatment options. We review current recommended management and treatment of capillary hemangiomas and discuss the benefits and risks of all previously reported treatment modalities.
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