Related Experiment Video
Updated: Jan 29, 2026
06:47
Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
Published on: September 27, 2017
10.1K
Report: A case report on Nevirapine induced exfoliative dermatitis
Thattakudian Sheikuduman Mohamed Saleem1, Kakavakam Jyothi1, S Chandra Babu2
1Drug Information Centre, Department of Pharmacy Practice, Annamacharya College of Pharmacy, Rajampet, India.
Pakistan Journal of Pharmaceutical Sciences
|February 18, 2019
Summary
Adverse drug reactions, including exfoliative dermatitis, are common with long-term HIV therapy. Nevirapine, a common HIV medication, can cause severe skin reactions, necessitating careful monitoring and treatment adjustments.
Area of Science:
- Dermatology
- Infectious Diseases
- Pharmacology
Background:
- Adverse drug reactions (ADRs) are a significant concern in long-term therapies, especially for immunocompromised patients.
- Dermatological reactions, ranging from rashes to severe conditions like Stevens-Johnson syndrome and exfoliative dermatitis, are frequently observed ADRs.
- Nevirapine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), is a first-line treatment for human immunodeficiency virus (HIV) infection.
Observation:
- This report details cases of severe exfoliative dermatitis.
- A patient with a three-year history of HIV treatment with Nevirapine presented with widespread skin scaling.
- Exfoliative dermatitis was diagnosed and strongly suspected to be induced by Nevirapine.
Findings:
- Nevirapine administration was linked to the development of severe exfoliative dermatitis in an HIV-positive patient.
- Discontinuation of Nevirapine and symptomatic treatment led to patient recovery.
- Alternative antiretroviral therapies were recommended post-recovery.
Implications:
- This case highlights the potential for severe dermatological ADRs with Nevirapine, even after prolonged use.
- Clinicians should maintain a high index of suspicion for Nevirapine-induced exfoliative dermatitis in HIV patients presenting with skin scaling.
- Prompt recognition and management, including drug cessation and supportive care, are crucial for favorable outcomes in Nevirapine-induced severe skin reactions.
Related Concept Videos
01:24Data Reporting and Recording
5.4K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K
01:25Types of Reports I: Hands-off Report
1.5K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
01:21Types of Reports II: Incident or Occurrence Report
1.2K
An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.2K
01:26Types of Reports III: Telephone and Verbal Reports
1.0K
Telephone and Verbal Reports in healthcare settings are two communication methods for conveying therapeutic instructions from healthcare providers to nurses or other healthcare staff.
Here's an overview of each type:
Telephone Orders
Here's an overview of each type:
Telephone Orders
1.0K
02:11Reporter Genes
13.2K
Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
13.2K
01:20Introduction to Documentation and Reporting
2.9K
Documentation is the systematic process of formally recording, maintaining, and communicating information.
Nursing documentation records essential information and details regarding a patient's care and treatment in written or electronic form. It is a critical aspect of nursing practice that involves documenting assessments, interventions, outcomes, and other relevant details about a patient's health status.
Documentation maps the patient's health journey by creating a comprehensive...
Nursing documentation records essential information and details regarding a patient's care and treatment in written or electronic form. It is a critical aspect of nursing practice that involves documenting assessments, interventions, outcomes, and other relevant details about a patient's health status.
Documentation maps the patient's health journey by creating a comprehensive...
2.9K